�ber die reflektorische Grundlage des Parkinsontremors
�ber die reflektorische Grundlage des Parkinsontremors
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Original abstract
1. The tension-reflex or the autogenic inhibition elicited by direct stimulation of a muscle has a duration of 80–100 msec in normal persons. In Parkinsonpatients the duration was found to be 120–180 msec. It is concluded that the augmentation of inhibitory influence is due to a change in the excitability of interneurons in the spinal cord. 2. It can be demonstrated that the silent periods between the impulse-groups of a Parkinson tremor are tension-reflexes or autogenic inhibitions. Therefore muscle-tension, experimentally added to a given time would prolong, but diminution of tension, if quick enough, would shorten the silent period of thise phase. 3. No signs of a central rhythm in Parkinsonian tremor can be shown. The rhythm must be proprioceptive. 4. Inhibitory impulses from one muscle are capable to influence the neuron-pools of the synergists. In this way autogenic inhibition of one muscle in Parkinson-patients can be the pace-maker for the others. So deafferentation of a muscle alone or a small group would be without important effect on the tremor rhythm.