ESTIMULAÇÃO CEREBRAL PROFUNDA NA DOENÇA DE PARKINSON: INDICAÇÕES CLÍNICAS E IMPACTO FUNCIONAL
ESTIMULAÇÃO CEREBRAL PROFUNDA NA DOENÇA DE PARKINSON: INDICAÇÕES CLÍNICAS E IMPACTO FUNCIONAL
Where did the research take place?
The study site has not been established. Author addresses may differ from where the research occurred.
A plain-language reading has not been prepared for this paper yet.
Original abstract
Parkinson’s disease is a progressive neurodegenerative disorder that significantly impairs motor function and patients’ quality of life. Although pharmacological treatment represents the cornerstone of initial management, disease progression often leads to the emergence of motor fluctuations and dyskinesias, limiting therapeutic effectiveness. In this context, deep brain stimulation (DBS) has become an effective alternative for appropriately selected patients. This chapter aimed to analyze, through a narrative literature review, the main indications for deep brain stimulation in Parkinson’s disease and its functional impact. The search was conducted in the PubMed, SciELO, ScienceDirect, and LILACS databases, including studies published between 2010 and 2025. The results indicate that DBS provides significant improvement in motor symptoms, reduction in “off” time, decreased need for dopaminergic medications, and meaningful gains in functionality and quality of life. It is also observed that the best outcomes are associated with careful patient selection, appropriate timing of the intervention, and multiprofessional follow-up. It is concluded that deep brain stimulation represents a well-established therapeutic tool in the management of Parkinson’s disease, with positive functional impact when integrated into continuous and individualized clinical care.