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Home-based deep sleep modulation in Parkinson's disease: extension study on long-term feasibility and sleep-related outcomes.

Home-based deep sleep modulation in Parkinson's disease: extension study on long-term feasibility and sleep-related outcomes.

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The study site has not been established. Author addresses may differ from where the research occurred.

Zürich, CH · Author affiliation

Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
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DE · Author affiliation · country only

Institute of Biomedical Engineering, Ulm University, Ulm, Germany.
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Original abstract

This study assessed feasibility and effects of a randomised two-week, at-home intervention with phase-targeted auditory stimulation (PTAS) of slow waves in Parkinson's disease (PD). We reproduced previously reported enhancement of slow wave activity and confirmed indications of improved patient-reported outcomes. Together with the high adherence and data quality, this suggests that home-based PTAS protocols are a feasible method for investigating the long-term therapeutic potential of deep sleep enhancement in PD.

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