Evaluating impulse control disorders in people with Parkinson's disease: agreement and added value of patient and caregiver reports.
Evaluating impulse control disorders in people with Parkinson's disease: agreement and added value of patient and caregiver reports.
Where did the research take place?
The study site has not been established. Author addresses may differ from where the research occurred.
Oslo, NO · Author affiliation
Department of Neurology, Oslo University Hospital, Oslo, Norway.Location evidence
NO · Author affiliation · country only
Department of Neurology, Akershus University Hospital, Nordbyhagen, Norway.Location evidence
Lund, SE · Author affiliation
Division of Neurology, Department of Clinical Sciences, Lund University, Lund, Sweden.Location evidence
Tromsø, NO · Author affiliation
Experimental and Clinical Pharmacology, Institute of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway.Location evidence
A plain-language reading has not been prepared for this paper yet.
Original abstract
BACKGROUND: People with Parkinson's Disease (PD) treated with dopamine agonists are at increased risk for developing impaired impulse control behavior. It has been suggested that patients tend to underreport problems with impaired impulse control, indicating that caregiver evaluations may be a helpful supplement to clinical assessment. OBJECTIVE: To examine the agreement between evaluations of impaired impulse control provided by people with PD treated with dopamine agonists and by their caregivers. METHODS: People with PD and their caregivers independently completed the validated Questionnaire for Impulse-Compulsive Disorders in Parkinson's Disease-Rating Scale (QUIP-RS) and the Impulse Control Disorders and Related Conditions (ICDRC) questionnaire. Patient and caregiver assessment were compared statistically for total scores and subscores on both questionnaires. RESULTS: Overall, patient and caregiver assessment on both the QUIP-RS and ICDRC showed no consistent systematic differences. Patients reported a slightly higher total ICDRC score and higher combined subscores for punding and dopamine dysregulation syndrome compared to their caregivers. Further, patient evaluations showed a wider range of responses for hypersexuality (QUIP-RS and ICDRC) and for gambling (ICDRC). CONCLUSION: The assessment of impaired impulse control remains difficult, and our findings indicate that the role of caregiver evaluations is still uncertain.