Therapeutic Potential of Macroalgae- and Microalgae-Derived Bioactive Compounds in Parkinson's Disease.
Therapeutic Potential of Macroalgae- and Microalgae-Derived Bioactive Compounds in Parkinson's Disease.
Where did the research take place?
The study site has not been established. Author addresses may differ from where the research occurred.
Kuala Lumpur, MY · Author affiliation
School of Health Sciences, IMU University, Kuala Lumpur, 57000, Malaysia.Location evidence
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Original abstract
Marine macroalgae and microalgae are valuable natural sources of diverse bioactive compounds, such as carbohydrates, phenolics, phycobiliproteins, carotenoids, fatty acids, and vitamins. These compounds exhibit a variety of biological activities, including anti-inflammatory, antioxidant, anticancer, and anti-apoptotic effects. Recently, increasing evidence has highlighted their neuroprotective potential, especially in the context of neurodegenerative disorders like Parkinson's disease (PD). This review summarizes the current understanding of the molecular mechanisms by which algal-derived bioactive compounds exert neuroprotective effects, based on findings from both in vitro and in vivo models of neuroinflammation and PD. Furthermore, we discuss the promising roles of these compounds as both disease-modifying agents and symptomatic therapies for PD.