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[Parkinson's Disease].

[Parkinson's Disease].

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Original abstract

Most patients with Parkinson's disease (PD) have sporadic disease, but some PD patients exhibit familial disease aggregation. Identification of causative genes and understanding their function and pathophysiology have contributed significantly to the diagnosis and treatment of PD. In this chapter, we explain the history of PD genetics and cutting-edge research findings, which genes should be tested, and how they should be tested in familial and typical sporadic PD in Japan.

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