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Proceedings of the 12th annual deep brain stimulation think tank: cutting edge technology meets novel applications.

Proceedings of the 12th annual deep brain stimulation think tank: cutting edge technology meets novel applications.

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The study site has not been established. Author addresses may differ from where the research occurred.

Norman, US · Author affiliation

Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
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Atlanta, US · Author affiliation

School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, United States.
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San Francisco, US · Author affiliation

Movement Disorders and Neuromodulation Centre, University of California San Francisco, San Francisco, CA, United States.
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Oxford, GB · Author affiliation

Medical Research Council Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
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Durham, US · Author affiliation

Departments of Biomedical Engineering, Electrical and Computer Engineering, Neurobiology and Neurosurgery, Duke University and Duke University Medical Center, Durham, NC, United States.
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US · Author affiliation · country only

Center for Neurological Restoration, Cleveland Clinic, Cleveland, OH, United States.
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New York City, US · Author affiliation

Weill Cornell Medical College, Feil Family Brain and Mind Research Institute, New York, NY, United States.
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Minneapolis, US · Author affiliation

Restorative Therapies Group Implantables, Research, and Core Technology, Medtronic Inc., Minneapolis, MN, United States.
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Los Angeles, US · Author affiliation

Department of Neurosurgery, University of California, Los Angeles, CA, United States.
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Boston, US · Author affiliation

Boston Scientific Neuromodulation, Valencia, CA, United States.
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Valencia, US · Author affiliation

Boston Scientific Neuromodulation, Valencia, CA, United States.
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Plano, US · Author affiliation

Neuromodulation Division, Abbott, Plano, TX, United States.
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Mountain View, US · Author affiliation

NeuroPace, Inc., Mountain View, CA, United States.
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Milan, IT · Author affiliation

Newronika SpA, Milan, Italy.
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Morgantown, US · Author affiliation

West Virginia University, Morgantown, WV, United States.
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Houston, US · Author affiliation

Department of Bioengineering, Rice University, Houston, TX, United States.
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Düsseldorf, DE · Author affiliation

Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
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London, GB · Author affiliation

Wellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, London, United Kingdom.
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Toronto, CA · Author affiliation

Clinical and Computational Neuroscience, Krembil Research Institute, University Health Network, Toronto, ON, Canada.
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Tübingen, DE · Author affiliation

Faculty of Medicine, Institute for Neuromodulation and Neurotechnology, University Hospital Tübingen (UKT), University Tübingen, Tübingen, Germany.
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Hopkins, US · Author affiliation

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
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Baltimore, US · Author affiliation

Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
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Philadelphia, US · Author affiliation

Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, United States.
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St. Louis, US · Author affiliation

Department of Neurology, Washington University School of Medicine, St. Louis, MO, United States.
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Changping, CN · Author affiliation

Changping Laboratory, Beijing, China.
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Beijing, CN · Author affiliation

Changping Laboratory, Beijing, China.
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Maastricht, NL · Author affiliation

School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.
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Aachen, DE · Author affiliation

Department of Neurosurgery, RWTH Aachen University Hospital, Aachen, Germany.
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Original abstract

The Deep Brain Stimulation (DBS) Think Tank XII was held on August 21st to 23rd. This year we showcased groundbreaking advancements in neuromodulation technology, focusing heavily on the novel uses of existing technology as well as next-generation technology. Our keynote speaker shared the vision of using neuro artificial intelligence to predict depression using brain electrophysiology. Innovative applications are currently being explored in stroke, disorders of consciousness, and sleep, while established treatments for movement disorders like Parkinson's disease are being refined with adaptive stimulation. Neuromodulation is solidifying its role in treating psychiatric disorders such as depression and obsessive-compulsive disorder, particularly for patients with treatment-resistant symptoms. We estimate that 300,000 leads have been implanted to date for neurologic and neuropsychiatric indications. Magnetoencephalography has provided insights into the post-DBS physiological changes. The field is also critically examining the ethical implications of implants, considering the long-term impacts on clinicians, patients, and manufacturers.

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