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[Influence of clozapine on neuroleptigenic extrapyramidal motor disturbances (author's transl)].

[Influence of clozapine on neuroleptigenic extrapyramidal motor disturbances (author's transl)].

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Original abstract

1. Human neuroleptogenic EPMS-disturbances are reversed by clozapine in animal experiments and in clinical use. This is consistent with the central anticholinergic efficacy of clozapine. 2. Clozapine seems to be a favourable concomitant medication when high dosage therapy of neuroleptics is applied--or at the incidence of dyskinesia.

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