RESEARCH / DISCOVERY
← Back to the library

[Early Detection of Manganese Intoxication Based on Occupational History and T1-weighted MRI].

[Early Detection of Manganese Intoxication Based on Occupational History and T1-weighted MRI].

Read the original publication

A plain-language reading has not been prepared for this paper yet.

Original abstract

Manganese regulates many enzymes and is essential for normal cell function. Chronic manganese intoxication has an insidious and progressive course terminating to atypical parkinsonism with little therapeutic efficacy. For subjects with chronic manganese exposure such as welders, manganese intoxication can be detected early based on the presence of hyperintensity in the globus pallidus on T(1)-weighted MRI and abnormally high urinary excretion of manganese with a chelating agent even in cases of normal serum/urine level of manganese.

Explore another example or bring your own paper

Pasted text and PDF extraction stay on this computer. The local guide explains terms and surfaces passages; rewriting requires a configured local model. Scanned PDFs need OCR first.

RECORD & PROVENANCE