[Intellectual impairments in patients with Parkinson's disease--a proposal of the subgroups of the disease].
[Intellectual impairments in patients with Parkinson's disease--a proposal of the subgroups of the disease].
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Original abstract
The severity of intellectual impairments of the 89 patients with Parkinson's disease was evaluated with Osaka Intelligence Scale for the Aged (OISA). They were divided into three groups; normal, slightly impaired, and demented using three discriminative functions of OISA. Their motor disabilities were rated on the Hoehn and Yahr's functional classification scale. EEG, psychotic symptoms such as visual hallucination and "leibhaftige Bewusstheit (K. Jaspers)", medications and prognosis for life were also examined. There was no significant correlation between the duration of the illness and the degree of their intellectual impairments. There were two specific subgroups among our samples; a group of patients who were demented rapidly after their onsets of parkinsonism, and a group of patients whose intelligence was preserved for a long period. The age of onset of the former group was older than the latter. The duration from the onset to death in the former was shorter than the latter. The former group of the patients exhibited psychotic symptoms and EEG abnormalities more frequently. The severity of motor disability and medication did not differ between two groups.