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[Therapy of idiopathic Parkinson syndrome 1817 to 2001. A success story?].

[Therapy of idiopathic Parkinson syndrome 1817 to 2001. A success story?].

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Original abstract

It lasted some 150 years after the first description by James Parkinson in 1817 until levodopa, the first really efficacious treatment, was available for Parkinson's disease. Previously only anticholinergic substances and stereotaxic operations, both acting merely exclusively on tremor, were used for many and a few years respectively. Even today the treatment is purely symptomatic. There is no treatment in sight which would cure the disease or at least stop or slow down its progression.

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